Tacrolimus Methylene Analog

Chemical Name: (3S, 4R, 5S, 8R, 12S, 14S, 15R, 16S, 18R, 19R, 26aS, E)-5, 19-Dihydroxy-3-((E)-1-((1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-methylallyl)-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-3H-15, 19-epoxypyrido[2, 1-c][1]oxa[4]azacyclotricosine-1, 7, 20, 21(4H, 23H)-tetraone

Smile: O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC(C)=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O